One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...

When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular aging, cancer, ...

A new study shows, for the first time, how the human genome folds and moves in 3D over time to control when genes turn on and ...

“Our lab is generally interested in discovering and characterizing previously unknown or poorly understood factors that are essential for genome maintenance. This is particularly important in the ...

MSK researchers are shedding new light on G-quadruplexes, a type of secondary DNA structure that can cause DNA replication to stall. The structures are a potential therapeutic target in cancer. Image ...

Deep in coastal mangroves and even inside our own mouths, biologists are finding that DNA does not always sit in a simple loop at the cell’s center. A giant microbe called Thiovulum imperiosus has now ...

Artificial intelligence has just redrawn the map of our genome’s control room, revealing hundreds of thousands of tiny DNA ...

Researchers have discovered how cells activate a last-resort DNA repair system when severe damage strikes. When genetic ...

If parent cells and their daughter cells are to share a stable identity, parent cells must divide—and replicate their DNA—while ensuring that their histones are distributed properly to their daughter ...