This is a preview. Log in through your library . Abstract A protein possessing both lac repressor and β -galactosidase activities in a single polypeptide of about 155,000 daltons was purified from a ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, No. 19 (May 10, 2005), pp. 6783-6788 (6 pages) A multiscale simulation of a complex between the lac repressor ...

Scientists have been trying to understand the nature and importance of protein-DNA interactions since the early 1960s. Such research started with studies of the association of RNA polymerase with DNA, ...

The lac Operon Explained In 1964, Jacob and Monod identified the promoter region for RNA polymerase. 9 A few years later, another team mapped the genes of the lac operon —the repressor, promoter, ...