Long before a liver tumor appears, a high-fat diet can push liver cells into a risky survival mode. That is the central ...

By recreating a fetal liver niche, FLOs show how liver and immune cells co-develop. Learn more about new groundbreaking research ...

Fatty liver disease isn’t just a concern for the overweight—it can strike people of healthy weight and diet, and now scientists think they know why. Two genes previously linked to cancer, RNF43 and ...

Scientists from Cincinnati Children's and colleagues based in Japan report achieving a major step forward in organoid technology: producing liver tissue that grows its own internal blood vessels. This ...

New MIT research uncovers how high-fat diets push liver cells into a primitive state, elevating cancer risk. Learn how fatty ...

Organoids refer to small-scale organs made up of diverse cell types, exhibiting structures and functions akin to actual organs. Unlike conventional cell cultures, organoids better replicate human ...

These synthetic compounds — known as per- and polyfluoroalkyl substances, or PFAS — could as much as triple the chances ...

Dr. Saurabh Sethi notes that most people believe sugar affects weight. However, it can strongly influence your liver.

The development of hepatocellular carcinoma, liver cancer, is known to involve abnormal activation of a signaling pathway called Wnt; however, the underlying mechanisms have not been fully understood, ...

Drugs that fail in late stages of development create one of the biggest challenges in global healthcare. In fact, less than 10% of the drugs that move into clinical development survive to approval.