JSTOR Daily

A Novel Marker Glycoprotein for the Microvillus Membrane of Surface Colonocytes of Rat Large Intestine and Its Presence in Small-Intestinal Crypt Cells

Murine mAbs were produced against purified microvillus membranes of rat colonocytes in order to establish a marker protein for this membrane. The majority of antibodies binding to the colonic ...
Labroots

Advanced Molecular Diagnostics for Microvillus Inclusion Disease

Microvillus inclusion disease (MVID) is a cause of chronic watery diarrhea that is attributed to a lack of nutrient absorption in the gastrointestinal tract in newborns. The disease can lead to ...
JSTOR Daily

The 110-kD Protein-Calmodulin Complex of the Intestinal Microvillus (Brush Border Myosin I) Is a Mechanoenzyme

The 110-kD protein-calmodulin complex (110K-CM) of the intestinal brush border serves to laterally tether microvillar actin filaments to the plasma membrane. Results from several laboratories have ...
Nature

Caught in the traffic

In mice, deletion of the Rab8 protein disrupts organized molecular distribution to membranes of intestinal epithelial cells. Death by starvation follows, exactly as it does in humans with microvillus ...
AZ Central

In Support of Possible Expedited Approval Pathway for Crofelemer for Treatment of Microvillus Inclusion Disease (MVID), Jaguar Health Submits Amended Protocol to FDA for ...

SAN FRANCISCO, CALIFORNIA / ACCESS Newswire / November 20, 2025 / Jaguar Health, Inc. (NASDAQ:JAGX) (Jaguar) family company Napo Pharmaceuticals (Napo) today announced that, in support of a possible ...