New research into the mechanism of the placebo effect sheds light on the brain circuitry involved in pain relief. The study, conducted by scientists at the University of North Carolina (UNC), Stanford ...

Pain represents the cardinal symptom of osteoarthritis, yet its intensity, quality, and impact vary dramatically among ...

Four tiny 3D organs connected themselves in a lab dish, forming a replica of the human pain pathway, in a new study. The discovery allows scientists to better understand chronic pain and how pain ...

Scientists have re-created a pain pathway in the brain by growing four key clusters of human nerve cells in a dish. This laboratory model could be used to help explain certain pain syndromes, and ...

This new article publication from Acta Pharmaceutica Sinica B, discusses allosteric modulation of G protein-coupled receptors as a novel therapeutic strategy in neuropathic pain. Neuropathic pain is a ...

Share on Pinterest A recent study used computational methods to identify novel compounds that activate receptors involved in pain modulation without sedation. Peter Dazeley/Getty Images Research on ...

Scientists created a model of the human pain pathway in a dish by connecting four separate brain organoids. The feat should help them understand sensory disorders like those affecting pain perception.

René Descartes gave a colorful description of the mechanism of pain in the 17th Century: "Particles" of fire set in motion a spot on the skin of the foot, and by means of a "delicate thread" they open ...