The human body has 78 organs and each one performs a variety of important functions. While it's possible to live without organs like the appendix, gallbladder, or spleen, several of our organs are ...

Approximately 1 in 11 patients with kidney failure requiring replacement therapy have inherited kidney diseases or congenital anomalies of the kidney and urinary tract. Genetic testing is warranted to ...

New global research shows that chronic kidney disease is climbing the ranks of leading causes of death, while millions of ...

Polycystic kidney disease (PKD) causes round, fluid-filled sacs called cysts to grow in your kidneys. These cysts can cause your kidneys to enlarge and function poorly. People with PKD can also ...

Nephrotic syndrome is a clinical entity defined by heavy proteinuria, hypoalbuminemia, hyperlipidemia, and edema, stemming from various glomerular diseases. Diagnosis requires a comprehensive ...

Medically reviewed by David Hampton, MD C3G is caused by immune system dysfunction that can lead to kidney issues.When the kidneys don't work as they should, people can experience blood or protein in ...

PKD is mainly caused by mutations in the PKD1 and PKD2 genes, affecting polycystin proteins. Disrupted signaling pathways, like cAMP and vasopressin, are major drivers of cyst growth. Tolvaptan is ...