A research team at Ruhr University Bochum, Germany, has identified a previously unknown cellular mechanism crucial to the replication of coronaviruses: c-Jun N-terminal kinase (JNK) is activated ...

A schematic diagram showing the significant contribution of SCoV2-induced altered mitochondrial dynamics and mitochondrial EGFR translocation in sustaining viral propagation. First, SCOV2 RNA and ...

High-resolution images provide clarity into how viral proteins are separated by a protease, an important step during virus replication that is targeted by an approved COVID-19 drug. UNIVERSITY PARK, ...

COVID-19, caused by severe acute respiratory coronavirus 2 (SARS-CoV-2), has presented a serious risk to global public health. The viral main protease Mpro (also called 3Clpro) encoded by NSP5 is an ...

The discovery could serve as a starting point for antiviral strategies. A research team at Ruhr University Bochum, Germany, has identified a previously unknown cellular mechanism crucial to the ...

In a recent study posted to the medRxiv* preprint server, researchers observe persistent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replication in severe coronavirus disease 2019 ...

To try to stay ahead of any future pandemics, scientists at Scripps Research in La Jolla are taking a deeper look into the proteins that coronaviruses depend on to survive. And with their findings, ...