Learn more about the “glue sniffer” protein, which is able to detect brain cells’ incoming chemical signals, and what that ...

Proteins that are no longer needed, defective, or potentially harmful are labeled with a molecular "tag" and dismantled in ...

Heterotrimeric G proteins, comprising Gα, Gβ and Gγ subunits, are central to the transduction of extracellular signals into precise intracellular responses in plants. These proteins not only regulate ...

A paper published in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel synthetic ligand that activates the Notch signaling pathway, a key driver in ...

Alzheimer's disease (AD) is a serious neurodegenerative disease largely affecting older adults. Apart from age, it also shows sex-based differences, with women being more at risk. However, the origin ...

The startup is developing a medicine that can very specifically degrade cancerous forms of EGFR, the target of an array of ...

Gastric cancer cells can activate KRAS-driven signals, enabling autonomous tumor growth by producing their own WNT proteins. New research reveals how gastric cancer cells exploit WNT signaling for ...

This review synthesizes clinical, genetic, and mechanistic evidence showing that suPAR and related uPAR fragments are ...

When the cell's recycling stations, the lysosomes, start leaking, it can become dangerous. Toxic waste risks spreading and ...

Researchers created a new kind of cancer drug that can grab a mutant protein while also carrying a second hit against the ...

A study led by researchers at Moffitt Cancer Center found that normal cells surrounding a tumor, known as cancer-associated ...